Cargando…

Transforming Growth Factor-β1 Induces Transdifferentiation of Myoblasts into Myofibroblasts via Up-Regulation of Sphingosine Kinase-1/S1P(3) Axis

The pleiotropic cytokine transforming growth factor (TGF)-β1 is a key player in the onset of skeletal muscle fibrosis, which hampers tissue repair. However, the molecular mechanisms implicated in TGFβ1-dependent transdifferentiation of myoblasts into myofibroblasts are presently unknown. Here, we sh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cencetti, Francesca, Bernacchioni, Caterina, Nincheri, Paola, Donati, Chiara, Bruni, Paola
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2010
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836962/ https://www.ncbi.nlm.nih.gov/pubmed/20089836 http://dx.doi.org/10.1091/mbc.E09-09-0812

Ejemplares similares

Sphingosine kinase/sphingosine 1-phosphate axis: a new player for insulin-like growth factor-1-induced myoblast differentiation
por: Bernacchioni, Caterina, et al.
Publicado: (2012)

NMR metabolomics highlights sphingosine kinase‐1 as a new molecular switch in the orchestration of aberrant metabolic phenotype in cancer cells
por: Bernacchioni, Caterina, et al.
Publicado: (2017)

Lysophosphatidic Acid Signaling Axis Mediates Ceramide 1-Phosphate-Induced Proliferation of C2C12 Myoblasts
por: Bernacchioni, Caterina, et al.
Publicado: (2018)

Ceramide 1-phosphate stimulates proliferation of C2C12 myoblasts
por: Gangoiti, Patricia, et al.
Publicado: (2012)

Role of Sphingosine 1-Phosphate Signalling Axis in Muscle Atrophy Induced by TNFα in C2C12 Myotubes
por: Bernacchioni, Caterina, et al.
Publicado: (2021)

Sphingosine 1-phosphate axis: a new leader actor in skeletal muscle biology
por: Donati, Chiara, et al.
Publicado: (2013)

The TRPV1 Receptor Is Up-Regulated by Sphingosine 1-Phosphate and Is Implicated in the Anandamide-Dependent Regulation of Mitochondrial Activity in C2C12 Myoblasts
por: Standoli, Sara, et al.
Publicado: (2022)

Sphingosine 1‐phosphate attenuates neuronal dysfunction induced by amyloid‐β oligomers through endocytic internalization of NMDA receptors
por: Bigi, Alessandra, et al.
Publicado: (2022)

Sphingosine 1-Phosphate Induces Differentiation of Mesoangioblasts towards Smooth Muscle. A Role for GATA6
por: Donati, Chiara, et al.
Publicado: (2011)

Sphingosine 1-phosphate signaling pathway in inner ear biology. New therapeutic strategies for hearing loss?
por: Romero-Guevara, Ricardo, et al.
Publicado: (2015)

S1P Signalling Axis Is Necessary for Adiponectin-Directed Regulation of Electrophysiological Properties and Oxidative Metabolism in C2C12 Myotubes
por: Bernacchioni, Caterina, et al.
Publicado: (2022)

A(2)(B) Adenosine Receptors and Sphingosine 1-Phosphate Signaling Cross-Talk in Oligodendrogliogenesis
por: Coppi, Elisabetta, et al.
Publicado: (2021)

An Active Form of Sphingosine Kinase-1 Is Released in the Extracellular Medium as Component of Membrane Vesicles Shed by Two Human Tumor Cell Lines
por: Rigogliuso, Salvatrice, et al.
Publicado: (2010)

Sphingosine kinase 1 is required for TGF-β mediated fibroblast-to-myofibroblast differentiation in ovarian cancer
por: Beach, Jessica A., et al.
Publicado: (2015)

Sphingosine kinase 1/sphingosine-1-phosphate (S1P)/S1P receptor axis is involved in ovarian cancer angiogenesis
por: Dai, Lan, et al.
Publicado: (2017)

Targeting the Sphingosine Kinase/Sphingosine-1-Phosphate Signaling Axis in Drug Discovery for Cancer Therapy
por: Gupta, Preeti, et al.
Publicado: (2021)

Adiponectin Modulates Smooth Muscle Cell Morpho-Functional Properties in Murine Gastric Fundus via Sphingosine Kinase 2 Activation
por: Garella, Rachele, et al.
Publicado: (2023)

Endometriosis: Cellular and Molecular Mechanisms Leading to Fibrosis
por: Garcia Garcia, Jose Manuel, et al.
Publicado: (2022)

MyoD induces ARTD1 and nucleoplasmic poly-ADP-ribosylation during fibroblast to myoblast transdifferentiation
por: Bisceglie, Lavinia, et al.
Publicado: (2021)

Inhibition of miR-29 by TGF-beta-Smad3 Signaling through Dual Mechanisms Promotes Transdifferentiation of Mouse Myoblasts into Myofibroblasts
por: Zhou, Liang, et al.
Publicado: (2012)

Histone Methyltransferase ASH1 Orchestrates Fibrogenic Gene Transcription During Myofibroblast Transdifferentiation
por: Perugorria, Maria Jesus, et al.
Publicado: (2012)

The role of the sphingosine axis in immune regulation: A dichotomy in the anti-inflammatory effects between sphingosine kinase 1 and sphingosine kinase 2-dependent pathways
por: Ishay, Yuval, et al.
Publicado: (2021)

Phosphatidic Acid Stimulates Myoblast Proliferation through Interaction with LPA1 and LPA2 Receptors
por: Gomez-Larrauri, Ana, et al.
Publicado: (2021)

Sphingosine Kinase 1 and Sphingosine-1-Phosphate Signaling in Colorectal Cancer
por: Bao, Yonghua, et al.
Publicado: (2017)

Telomere dysfunction promotes transdifferentiation of human fibroblasts into myofibroblasts
por: Razdan, Neetu, et al.
Publicado: (2018)

The signal pathway for the repressive effect of dipyridamole on myofibroblast transdifferentiation
por: Yan, Qiong, et al.
Publicado: (2018)

P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression
por: Li, Haisheng, et al.
Publicado: (2016)

JNK and p38 Inhibitors Prevent Transforming Growth Factor-β1-Induced Myofibroblast Transdifferentiation in Human Graves’ Orbital Fibroblasts
por: Hou, Tzu-Yu, et al.
Publicado: (2021)

Transdifferentiation of Myoblasts Into Adipocytes by All-Trans-Retinoic Acid in Avian
por: Kim, Dong-Hwan, et al.
Publicado: (2022)

The Role of Focal Adhesion Kinase in the TGF-β-Induced Myofibroblast Transdifferentiation of Human Tenon's Fibroblasts
por: Hong, Samin, et al.
Publicado: (2012)

Arecoline-induced myofibroblast transdifferentiation from human buccal mucosal fibroblasts is mediated by ZEB1
por: Chang, Yu-Chao, et al.
Publicado: (2014)

MEK inhibition prevents TGF-β1-induced myofibroblast transdifferentiation in human tenon fibroblasts
por: Wen, Jiamin, et al.
Publicado: (2019)

Lefty-1 alleviates TGF-β1-induced fibroblast–myofibroblast transdifferentiation in NRK-49F cells
por: Zhang, Lijun, et al.
Publicado: (2015)

Interaction of microRNAs with sphingosine kinases, sphingosine-1 phosphate, and sphingosine-1 phosphate receptors in cancer
por: Xu, Guangmeng, et al.
Publicado: (2021)

Insulin Protects Apoptotic Cardiomyocytes from Hypoxia/Reoxygenation Injury through the Sphingosine Kinase/Sphingosine 1-Phosphate Axis
por: Yu, Huan, et al.
Publicado: (2013)

Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2016)

Effects of cyclosporin, nifedipine and phenytoin on gingival myofibroblast transdifferentiation in monkeys
por: Kanno, Claudia Misue, et al.
Publicado: (2018)

Loss of MyoD Promotes Fate Transdifferentiation of Myoblasts Into Brown Adipocytes
por: Wang, Chao, et al.
Publicado: (2017)

Commentary: The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension
por: Bhavanam, Naga P., et al.
Publicado: (2015)

Impairment of Angiogenic Sphingosine Kinase-1/Sphingosine-1-Phosphate Receptors Pathway in Preeclampsia
por: Dobierzewska, Aneta, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_kr0dk6fgqn8l2sjiea90c2a004