The RhoA Activator GEF-H1/Lfc Is a Transforming Growth Factor-β Target Gene and Effector That Regulates α-Smooth Muscle Actin Expression and Cell Migration

Maintenance of the epithelial phenotype is crucial for tissue homeostasis. In the retina, dedifferentiation and loss of integrity of the retinal pigment epithelium (RPE) leads to retinal dysfunction and fibrosis. Transforming growth factor (TGF)-β critically contributes to RPE dedifferentiation and...

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Detalles Bibliográficos
Autores principales: Tsapara, Anna, Luthert, Phillip, Greenwood, John, Hill, Caroline S., Matter, Karl, Balda, Maria S.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836967/
https://www.ncbi.nlm.nih.gov/pubmed/20089843
http://dx.doi.org/10.1091/mbc.E09-07-0567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836967/
https://www.ncbi.nlm.nih.gov/pubmed/20089843
http://dx.doi.org/10.1091/mbc.E09-07-0567

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