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Requirements and Reasons for Effective Inhibition of the Anaphase Promoting Complex Activator Cdh1
Anaphase promoting complex (APC)-Cdh1 targets multiple mitotic proteins for degradation upon exit from mitosis into G1; inhibitory phosphorylation of Cdh1 by cyclin-dependent kinase (CDK) and Polo kinase has been proposed to prevent the premature degradation of substrates in the ensuing cell cycle....
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836972/ https://www.ncbi.nlm.nih.gov/pubmed/20089834 http://dx.doi.org/10.1091/mbc.E09-10-0901 |