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Requirements and Reasons for Effective Inhibition of the Anaphase Promoting Complex Activator Cdh1

Anaphase promoting complex (APC)-Cdh1 targets multiple mitotic proteins for degradation upon exit from mitosis into G1; inhibitory phosphorylation of Cdh1 by cyclin-dependent kinase (CDK) and Polo kinase has been proposed to prevent the premature degradation of substrates in the ensuing cell cycle....

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Detalles Bibliográficos
Autores principales:	Robbins, Jonathan A., Cross, Frederick R.
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2010
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836972/ https://www.ncbi.nlm.nih.gov/pubmed/20089834 http://dx.doi.org/10.1091/mbc.E09-10-0901

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