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Poleward Transport of TPX2 in the Mammalian Mitotic Spindle Requires Dynein, Eg5, and Microtubule Flux

TPX2 is a Ran-regulated spindle assembly factor that is required for kinetochore fiber formation and activation of the mitotic kinase Aurora A. TPX2 is enriched near spindle poles and is required near kinetochores, suggesting that it undergoes dynamic relocalization throughout mitosis. Using photoac...

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Detalles Bibliográficos
Autores principales:	Ma, Nan, Tulu, U. S., Ferenz, Nick P., Fagerstrom, Carey, Wilde, Andrew, Wadsworth, Patricia
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2010
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836978/ https://www.ncbi.nlm.nih.gov/pubmed/20110350 http://dx.doi.org/10.1091/mbc.E09-07-0601

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