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Sialic acid mediated transcriptional modulation of a highly conserved sialometabolism gene cluster in Haemophilus influenzae and its effect on virulence
BACKGROUND: Sialic acid has been shown to be a major virulence determinant in the pathogenesis of otitis media caused by the bacterium Haemophilus influenzae. This study aimed to characterise the expression of genes required for the metabolism of sialic acid and to investigate the role of these gene...
Autores principales: | Jenkins, Gaynor A, Figueira, Marisol, Kumar, Gaurav A, Sweetman, Wendy A, Makepeace, Katherine, Pelton, Stephen I, Moxon, Richard, Hood, Derek W |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836998/ https://www.ncbi.nlm.nih.gov/pubmed/20158882 http://dx.doi.org/10.1186/1471-2180-10-48 |
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