Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors

A dry extract from the roots of rhapontic rhubarb (extract Rheum rhaponticum (L.); ERr) has been commercially available in Germany for over two decades to treat menopausal symptoms. However, the molecular basis of its clinical effectiveness remains obscure. This article reviews the in vitro and in v...

Descripción completa

Detalles Bibliográficos
Autores principales: Vollmer, Günter, Papke, Anja, Zierau, Oliver
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837008/
https://www.ncbi.nlm.nih.gov/pubmed/20170496
http://dx.doi.org/10.1186/1749-8546-5-7
_version_ 1782178758499762176
author Vollmer, Günter
Papke, Anja
Zierau, Oliver
author_facet Vollmer, Günter
Papke, Anja
Zierau, Oliver
author_sort Vollmer, Günter
collection PubMed
description A dry extract from the roots of rhapontic rhubarb (extract Rheum rhaponticum (L.); ERr) has been commercially available in Germany for over two decades to treat menopausal symptoms. However, the molecular basis of its clinical effectiveness remains obscure. This article reviews the in vitro and in vivo data of its estrogenic actions, particularly those mediated by estrogen receptor-β (ERβ).
format Text
id pubmed-2837008
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-28370082010-03-12 Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors Vollmer, Günter Papke, Anja Zierau, Oliver Chin Med Review A dry extract from the roots of rhapontic rhubarb (extract Rheum rhaponticum (L.); ERr) has been commercially available in Germany for over two decades to treat menopausal symptoms. However, the molecular basis of its clinical effectiveness remains obscure. This article reviews the in vitro and in vivo data of its estrogenic actions, particularly those mediated by estrogen receptor-β (ERβ). BioMed Central 2010-02-19 /pmc/articles/PMC2837008/ /pubmed/20170496 http://dx.doi.org/10.1186/1749-8546-5-7 Text en Copyright ©2010 Vollmer et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Vollmer, Günter
Papke, Anja
Zierau, Oliver
Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors
title Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors
title_full Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors
title_fullStr Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors
title_full_unstemmed Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors
title_short Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors
title_sort treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837008/
https://www.ncbi.nlm.nih.gov/pubmed/20170496
http://dx.doi.org/10.1186/1749-8546-5-7
work_keys_str_mv AT vollmergunter treatmentofmenopausalsymptomsbyanextractfromtherootsofrhaponticrhubarbtheroleofestrogenreceptors
AT papkeanja treatmentofmenopausalsymptomsbyanextractfromtherootsofrhaponticrhubarbtheroleofestrogenreceptors
AT zierauoliver treatmentofmenopausalsymptomsbyanextractfromtherootsofrhaponticrhubarbtheroleofestrogenreceptors

Ejemplares similares