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Apolipoprotein-E forms dimers in human frontal cortex and hippocampus

BACKGROUND: Apolipoprotein-E (apoE) plays important roles in neurobiology and the apoE4 isoform increases risk for Alzheimer's disease (AD). ApoE3 and apoE2 are known to form disulphide-linked dimers in plasma and cerebrospinal fluid whereas apoE4 cannot form these dimers as it lacks a cysteine...

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Detalles Bibliográficos
Autores principales:	Elliott, David A, Halliday, Glenda M, Garner, Brett
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837047/ https://www.ncbi.nlm.nih.gov/pubmed/20170526 http://dx.doi.org/10.1186/1471-2202-11-23

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