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The IGF-1/IGF-1R signaling axis in the skin: a new role for the dermis in aging-associated skin cancer

The appropriate response of human keratinocytes to UVB is dependent on the activation status of the IGF-1 receptor. Keratinocytes grown in conditions where the IGF-1 receptor is inactive, inappropriately replicate in the presence of UVB-induced DNA damage. In human skin epidermal keratinocytes do no...

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Detalles Bibliográficos
Autores principales:	Lewis, Davina A., Travers, Jeffrey B., Somani, Ally-Khan, Spandau, Dan F
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837099/ https://www.ncbi.nlm.nih.gov/pubmed/19966862 http://dx.doi.org/10.1038/onc.2009.440

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