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Identification of Peptide Ligands for Targeting to the Blood-Brain Barrier

PURPOSE: Transport of drugs to the brain is limited by the blood-brain barrier. New, specific brain endothelium ligands can facilitate brain-specific delivery of drugs. METHODS: We used phage display in an in situ brain perfusion model to screen for new brain endothelium peptide ligands. RESULTS: Tw...

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Detalles Bibliográficos
Autores principales:	van Rooy, Inge, Cakir-Tascioglu, Serpil, Couraud, Pierre-Olivier, Romero, Ignacio A., Weksler, Babette, Storm, Gert, Hennink, Wim E., Schiffelers, Raymond M., Mastrobattista, Enrico
Formato:	Texto
Lenguaje:	English
Publicado:	Springer US 2010
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837178/ https://www.ncbi.nlm.nih.gov/pubmed/20162339 http://dx.doi.org/10.1007/s11095-010-0053-6

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