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A Model-Based Methodology for Spray-Drying Process Development
Solid amorphous dispersions are frequently used to improve the solubility and, thus, the bioavailability of poorly soluble active pharmaceutical ingredients (APIs). Spray-drying, a well-characterized pharmaceutical unit operation, is ideally suited to producing solid amorphous dispersions due to its...
Autores principales: | Dobry, Dan E., Settell, Dana M., Baumann, John M., Ray, Rod J., Graham, Lisa J., Beyerinck, Ron A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer US
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837209/ https://www.ncbi.nlm.nih.gov/pubmed/20234866 http://dx.doi.org/10.1007/s12247-009-9064-4 |
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