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A Model-Based Methodology for Spray-Drying Process Development

Solid amorphous dispersions are frequently used to improve the solubility and, thus, the bioavailability of poorly soluble active pharmaceutical ingredients (APIs). Spray-drying, a well-characterized pharmaceutical unit operation, is ideally suited to producing solid amorphous dispersions due to its...

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Detalles Bibliográficos
Autores principales: Dobry, Dan E., Settell, Dana M., Baumann, John M., Ray, Rod J., Graham, Lisa J., Beyerinck, Ron A.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2009
Materias:
 
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837209/
https://www.ncbi.nlm.nih.gov/pubmed/20234866
http://dx.doi.org/10.1007/s12247-009-9064-4

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