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Epimutations, Inheritance and Causes of Aberrant DNA Methylation in Cancer
Epigenetic aberrations such as global hypomethylation and gene-specific hypermethylation are key events that underlie tumour development. Such scenarios are brought about by the loss of control of methylation patterns which typically are reversed in neoplasia in comparison to normal states. Despite...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837289/ https://www.ncbi.nlm.nih.gov/pubmed/20223011 http://dx.doi.org/10.1186/1897-4287-4-2-75 |