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A Role for Methyl-CpG Binding Domain Protein 2 in the Modulation of the Estrogen Response of pS2/TFF1 Gene

BACKGROUND: In human Estrogen Receptor α (ERα)-positive breast cancers, 5′ end dense methylation of the estrogen-regulated pS2/TFF1 gene correlates with its transcriptional inhibition. However, in some ERα-rich biopsies, pS2 expression is observed despite the methylation of its TATA-box region. Here...

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Detalles Bibliográficos
Autores principales:	Chatagnon, Amandine, Ballestar, Esteban, Esteller, Manel, Dante, Robert
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837351/ https://www.ncbi.nlm.nih.gov/pubmed/20300195 http://dx.doi.org/10.1371/journal.pone.0009665

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