Serum Amyloid P Therapeutically Attenuates Murine Bleomycin-Induced Pulmonary Fibrosis via Its Effects on Macrophages

Macrophages promote tissue remodeling but few mechanisms exist to modulate their activity during tissue fibrosis. Serum amyloid P (SAP), a member of the pentraxin family of proteins, signals through Fcγ receptors which are known to affect macrophage activation. We determined that IPF/UIP patients ha...

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Detalles Bibliográficos
Autores principales: Murray, Lynne A., Rosada, Rogerio, Moreira, Ana Paula, Joshi, Amrita, Kramer, Michael S., Hesson, David P., Argentieri, Rochelle L., Mathai, Susan, Gulati, Mridu, Herzog, Erica L., Hogaboam, Cory M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837381/
https://www.ncbi.nlm.nih.gov/pubmed/20300636
http://dx.doi.org/10.1371/journal.pone.0009683

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