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Dynamic Imaging of Experimental Leishmania donovani-Induced Hepatic Granulomas Detects Kupffer Cell-Restricted Antigen Presentation to Antigen-Specific CD8(+) T Cells

Kupffer cells (KCs) represent the major phagocytic population within the liver and provide an intracellular niche for the survival of a number of important human pathogens. Although KCs have been extensively studied in vitro, little is known of their in vivo response to infection and their capacity...

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Detalles Bibliográficos
Autores principales: Beattie, Lynette, Peltan, Adam, Maroof, Asher, Kirby, Alun, Brown, Najmeeyah, Coles, Mark, Smith, Deborah F., Kaye, Paul M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837408/
https://www.ncbi.nlm.nih.gov/pubmed/20300603
http://dx.doi.org/10.1371/journal.ppat.1000805