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Prevalent positive epistasis in E. coli and S. cerevisiae metabolic networks
Epistasis refers to the interaction between genes. Although high-throughput epistasis data from model organisms are being generated and used to construct genetic networks1-3, to what extent genetic epistasis reflects biologically meaningful interactions remains unclear4-6. We address this question b...
Autores principales: | He, Xionglei, Qian, Wenfeng, Wang, Zhi, Li, Ying, Zhang, Jianzhi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837480/ https://www.ncbi.nlm.nih.gov/pubmed/20101242 http://dx.doi.org/10.1038/ng.524 |
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