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Comparison of the ‘Denver regimen’ against acute tuberculosis in the mouse and guinea pig

OBJECTIVES: In this study, we sought to compare the sterilizing activity of human-equivalent doses of the ‘Denver regimen’ against acute tuberculosis (TB) infection in the standard mouse model and in the guinea pig. METHODS: Pharmacokinetic studies in guinea pigs were used to establish human-equival...

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Detalles Bibliográficos
Autores principales:	Ahmad, Zahoor, Nuermberger, Eric L., Tasneen, Rokeya, Pinn, Michael L., Williams, Kathy N., Peloquin, Charles A., Grosset, Jacques H., Karakousis, Petros C.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837551/ https://www.ncbi.nlm.nih.gov/pubmed/20123722 http://dx.doi.org/10.1093/jac/dkq007

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