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Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers

BACKGROUND: Altered DNA repair may be associated with aggressive tumour biology and impact upon response to chemotherapy and radiotherapy. We investigated whether expression of human AP endonuclease (APE1), a key multifunctional protein involved in DNA BER, would impact on clinicopathological outcom...

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Detalles Bibliográficos
Autores principales:	Al-Attar, A, Gossage, L, Fareed, K R, Shehata, M, Mohammed, M, Zaitoun, A M, Soomro, I, Lobo, D N, Abbotts, R, Chan, S, Madhusudan, S
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837561/ https://www.ncbi.nlm.nih.gov/pubmed/20087352 http://dx.doi.org/10.1038/sj.bjc.6605541

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