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Expansion of anti-AFP Th1 and Tc1 responses in hepatocellular carcinoma occur in different stages of disease

BACKGROUND: α-Fetoprotein (AFP) is a tumour-associated antigen in hepatocellular carcinoma (HCC) and is a target for immunotherapy. However, there is little information on the pattern of CD4 (Th1) and CD8 (Tc1) T-cell response to AFP in patients with HCC and their association with the clinical chara...

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Detalles Bibliográficos
Autores principales:	Behboudi, S, Alisa, A, Boswell, S, Anastassiou, J, Pathan, A A, Williams, R
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837570/ https://www.ncbi.nlm.nih.gov/pubmed/20087354 http://dx.doi.org/10.1038/sj.bjc.6605526

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