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Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells

BACKGROUND: Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) induces tumour cell apoptosis by binding to death receptor 4 (DR4) and DR5. DR4 and DR5 activation however can also induce inflammatory and pro-survival signalling. It is not known how these different cellular responses are...

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Detalles Bibliográficos
Autores principales:	Mahalingam, D, Natoni, A, Keane, M, Samali, A, Szegezdi, E
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837577/ https://www.ncbi.nlm.nih.gov/pubmed/20087343 http://dx.doi.org/10.1038/sj.bjc.6605545

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