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Cyclooxygenase-2 enhances α2β1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells

BACKGROUND: Cyclooxygenase (COX)-2, the inducible isoform of prostaglandin (PG) synthase, has been implicated in tumor metastasis. Interaction of COX-2 with its specific EP receptors on the surface of cancer cells has been reported to induce cancer invasion. However, the effects of COX-2 on migratio...

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Detalles Bibliográficos
Autores principales: Liu, Ju-Fang, Fong, Yi-Chin, Chang, Chih-Shiang, Huang, Chun-Yin, Chen, Hsien-Te, Yang, Wei-Hung, Hsu, Chin-Jung, Jeng, Long-Bin, Chen, Chih-Yi, Tang, Chih-Hsin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837621/
https://www.ncbi.nlm.nih.gov/pubmed/20178602
http://dx.doi.org/10.1186/1476-4598-9-43