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A New Statistic to Evaluate Imputation Reliability

BACKGROUND: As the amount of data from genome wide association studies grows dramatically, many interesting scientific questions require imputation to combine or expand datasets. However, there are two situations for which imputation has been problematic: (1) polymorphisms with low minor allele freq...

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Detalles Bibliográficos
Autores principales:	Lin, Peng, Hartz, Sarah M., Zhang, Zhehao, Saccone, Scott F., Wang, Jia, Tischfield, Jay A., Edenberg, Howard J., Kramer, John R., M.Goate, Alison, Bierut, Laura J., Rice, John P.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837741/ https://www.ncbi.nlm.nih.gov/pubmed/20300623 http://dx.doi.org/10.1371/journal.pone.0009697

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