A Dominant-Negative PPARγ Mutant Promotes Cell Cycle Progression and Cell Growth in Vascular Smooth Muscle Cells

PPARγ ligands have been shown to have antiproliferative effects on many cell types. We herein report that a synthetic dominant-negative (DN) PPARγ mutant functions like a growth factor to promote cell cycle progression and cell proliferation in human coronary artery smooth muscle cells (CASMCs). In...

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Detalles Bibliográficos
Autores principales: Liu, Joey Z., Lyon, Christopher J., Hsueh, Willa A., Law, Ronald E.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837897/
https://www.ncbi.nlm.nih.gov/pubmed/20300579
http://dx.doi.org/10.1155/2009/438673

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