Aberrant Methylation of Thrombospondin-1 and Its Association with Reduced Expression in Gastric Cardia Adenocarcinoma

Aim. Investigate the promoter methylation of the Thrombospondin-1 (TSP1) gene in gastric cardia adenocarcinoma (GCA). Methods. MSP approach, immunohistochemistry method, and RT-PCR were used respectively to examine the promoter methylation of TSP1, its protein and mRNA expression in tumors and corre...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Dong, Zhiming, He, Ming, Guo, Yanli, Guo, Jianwen, Chen, Zhifeng, Yang, Zhibin, Kuang, Gang
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838370/
https://www.ncbi.nlm.nih.gov/pubmed/20300551
http://dx.doi.org/10.1155/2010/721485

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