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Sequestration of the Aβ Peptide Prevents Toxicity and Promotes Degradation In Vivo
Protein aggregation, arising from the failure of the cell to regulate the synthesis or degradation of aggregation-prone proteins, underlies many neurodegenerative disorders. However, the balance between the synthesis, clearance, and assembly of misfolded proteins into neurotoxic aggregates remains p...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838747/ https://www.ncbi.nlm.nih.gov/pubmed/20305716 http://dx.doi.org/10.1371/journal.pbio.1000334 |