NADPH Oxidase Limits Innate Immune Responses in the Lungs in Mice

BACKGROUND: Chronic granulomatous disease (CGD), an inherited disorder of the NADPH oxidase in which phagocytes are defective in generating superoxide anion and downstream reactive oxidant intermediates (ROIs), is characterized by recurrent bacterial and fungal infections and by excessive inflammati...

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Detalles Bibliográficos
Autores principales: Segal, Brahm H., Han, Wei, Bushey, Jennifer J., Joo, Myungsoo, Bhatti, Zahida, Feminella, Joy, Dennis, Carly G., Vethanayagam, R. Robert, Yull, Fiona E., Capitano, Maegan, Wallace, Paul K., Minderman, Hans, Christman, John W., Sporn, Michael B., Chan, Jefferson, Vinh, Donald C., Holland, Steven M., Romani, Luigina R., Gaffen, Sarah L., Freeman, Michael L., Blackwell, Timothy S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838778/
https://www.ncbi.nlm.nih.gov/pubmed/20300512
http://dx.doi.org/10.1371/journal.pone.0009631

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