Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells

BACKGROUND: Sulforaphane (SFN), an isothiocyanate phytochemical present predominantly in cruciferous vegetables such as brussels sprout and broccoli, is considered a promising chemo-preventive agent against cancer. In-vitro exposure to SFN appears to result in the induction of apoptosis and cell-cyc...

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Detalles Bibliográficos
Autores principales: Bryant, Christopher S, Kumar, Sanjeev, Chamala, Sreedhar, Shah, Jay, Pal, Jagannath, Haider, Mahdi, Seward, Shelly, Qazi, Aamer M, Morris, Robert, Semaan, Assaad, Shammas, Masood A, Steffes, Christopher, Potti, Ravindra B, Prasad, Madhu, Weaver, Donald W, Batchu, Ramesh B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838815/
https://www.ncbi.nlm.nih.gov/pubmed/20196847
http://dx.doi.org/10.1186/1476-4598-9-47

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