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Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
BACKGROUND: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical questions. Statistical and computational methods are key for drawing meaningful and accurate conclusions from the massive and com...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838869/ https://www.ncbi.nlm.nih.gov/pubmed/20167110 http://dx.doi.org/10.1186/1471-2105-11-94 |