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Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response
BACKGROUND: The quasispecies nature of HCV may have important implications for viral persistence, pathogenicity and resistance to antiviral agents. The variability of one of the viral proteins, NS5A, is believed to be related to the response to IFN therapy, the standard treatment for infection. In t...
Autores principales: | Bittar, Cíntia, Jardim, Ana Carolina G, Yamasaki, Lilian HT, de Queiróz, Artur TL, Carareto, Claudia MA, Pinho, João Renato R, de Carvalho-Mello, Isabel Maria VG, Rahal, Paula |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838888/ https://www.ncbi.nlm.nih.gov/pubmed/20178583 http://dx.doi.org/10.1186/1471-2334-10-36 |
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