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Neuroprotective effects of bis(7)-tacrine against glutamate-induced retinal ganglion cells damage
BACKGROUND: Glutamate-mediated excitotoxicity, primarily through N-methyl-D-aspartate (NMDA) receptors, may be an important cause of retinal ganglion cells (RGCs) death in glaucoma and several other retinal diseases. Bis(7)-tacrine is a noncompetitive NMDA receptors antagonist that can prevent gluta...
Autores principales: | Fang, Jia Hua, Wang, Xing Hua, Xu, Zhi Rong, Jiang, Fa Gang |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838896/ https://www.ncbi.nlm.nih.gov/pubmed/20199668 http://dx.doi.org/10.1186/1471-2202-11-31 |
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