Cargando…
Hepatic steatosis in hepatitis C is a storage disease due to HCV interaction with microsomal triglyceride transfer protein (MTP)
Liver steatosis is a frequent histological feature in patients chronically infected with hepatitis C virus (HCV). The relationship between HCV and hepatic steatosis seems to be the result of both epigenetic and genetic factors. In vivo and in vitro studies have shown that HCV can alter intrahepatic...
Autores principales: | Mirandola, Silvia, Bowman, David, Hussain, Mahmood M, Alberti, Alfredo |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838899/ https://www.ncbi.nlm.nih.gov/pubmed/20178560 http://dx.doi.org/10.1186/1743-7075-7-13 |
Ejemplares similares
-
JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs
por: Aggarwal, Dimple, et al.
Publicado: (2005) -
Genetic variation in the microsomal triglyceride transfer protein (−493G/T) is associated with hepatic steatosis in patients infected with hepatitis C virus
por: Magri, Mariana Cavalheiro, et al.
Publicado: (2017) -
Microsomal Triglyceride Transfer Protein (MTP) Associates with Cytosolic Lipid Droplets in 3T3-L1 Adipocytes
por: Love, Joseph D., et al.
Publicado: (2015) -
Multiple functions of microsomal triglyceride transfer protein
por: Hussain, M Mahmood, et al.
Publicado: (2012) -
Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein
por: Anaganti, Narasimha, et al.
Publicado: (2022)