Ileocaecal recurrence of Merkel cell carcinoma of the skin: a case report

INTRODUCTION: Merkel cell carcinoma is an uncommon skin malignancy that has a high propensity for metastatic spread. A systematic literature search identified 17 cases describing metastasis to the gastrointestinal tract, with 7 cases involving the small or large bowel. To the best of our knowledge,...

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Detalles Bibliográficos
Autores principales: Cheung, Michelle, Lee, Henry, Purkayastha, Sanjay, Goldin, Robert, Ziprin, Paul
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Case report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838912/
https://www.ncbi.nlm.nih.gov/pubmed/20181112
http://dx.doi.org/10.1186/1752-1947-4-43
Descripción
Sumario:INTRODUCTION: Merkel cell carcinoma is an uncommon skin malignancy that has a high propensity for metastatic spread. A systematic literature search identified 17 cases describing metastasis to the gastrointestinal tract, with 7 cases involving the small or large bowel. To the best of our knowledge, this is the only case described of Merkel cell carcinoma metastasising to the ileocaecal valve. CASE PRESENTATION: We present a 74-year-old Filipino woman diagnosed with Merkel cell carcinoma of the skin with regional node involvement. Following excision and radiotherapy, the tumour recurred with metastasis to the ileocaecal valve. The patient died 28 months after the initial diagnosis. CONCLUSION: The prognosis of metastatic Merkel cell carcinoma is poor. Currently the optimal management for metastatic disease is unclear and lacks a firm evidence base due to the small number of cases reported.

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