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Anti-inflammatory effects of nicotinic acid in adipocytes demonstrated by suppression of fractalkine, RANTES, and MCP-1 and upregulation of adiponectin

OBJECTIVE: A major site of action for the atheroprotective drug nicotinic acid (NA) is adipose tissue, via the G-protein-coupled receptor, GPR109A. Since, adipose tissue is an active secretory organ that contributes both positively and negatively to systemic inflammatory processes associated with ca...

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Detalles Bibliográficos
Autores principales:	Digby, Janet E., McNeill, Eileen, Dyar, Oliver J., Lam, Vincent, Greaves, David R., Choudhury, Robin P.
Formato:	Texto
Lenguaje:	English
Publicado:	Elsevier 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839075/ https://www.ncbi.nlm.nih.gov/pubmed/19781706 http://dx.doi.org/10.1016/j.atherosclerosis.2009.08.045

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