Study of glucose uptake activity of Helicteres isora Linn. fruits in L-6 cell lines

The effect of hot water extract of fruits of Helicteres isora on glucose uptake was studied in rodent skeletal muscle cells (L-6 cells) involved in glucose utilization. H. isora is an antidiabetic medicinal plant being used in Indian traditional medicine. Hot water extracts were analysed for glucose...

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Detalles Bibliográficos
Autores principales: Gupta, R. N., Pareek, Anil, Suthar, Manish, Rathore, Garvendra S., Basniwal, Pawan K., Jain, Deepti
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839132/
https://www.ncbi.nlm.nih.gov/pubmed/20336200
http://dx.doi.org/10.4103/0973-3930.57349
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author Gupta, R. N.
Pareek, Anil
Suthar, Manish
Rathore, Garvendra S.
Basniwal, Pawan K.
Jain, Deepti
author_facet Gupta, R. N.
Pareek, Anil
Suthar, Manish
Rathore, Garvendra S.
Basniwal, Pawan K.
Jain, Deepti
author_sort Gupta, R. N.
collection PubMed
description The effect of hot water extract of fruits of Helicteres isora on glucose uptake was studied in rodent skeletal muscle cells (L-6 cells) involved in glucose utilization. H. isora is an antidiabetic medicinal plant being used in Indian traditional medicine. Hot water extracts were analysed for glucose uptake activity and found to be significantly active at 200 μg/ml dose comparable with insulin and metformin. Elevation of glucose uptake by H. isora in association with glucose transport supported the upregulation of glucose uptake. It was concluded that hot water extract of H. isora activate glucose uptake in L-6 cell line of mouse skeletal muscles.
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spelling pubmed-28391322010-03-24 Study of glucose uptake activity of Helicteres isora Linn. fruits in L-6 cell lines Gupta, R. N. Pareek, Anil Suthar, Manish Rathore, Garvendra S. Basniwal, Pawan K. Jain, Deepti Int J Diabetes Dev Ctries Original Article The effect of hot water extract of fruits of Helicteres isora on glucose uptake was studied in rodent skeletal muscle cells (L-6 cells) involved in glucose utilization. H. isora is an antidiabetic medicinal plant being used in Indian traditional medicine. Hot water extracts were analysed for glucose uptake activity and found to be significantly active at 200 μg/ml dose comparable with insulin and metformin. Elevation of glucose uptake by H. isora in association with glucose transport supported the upregulation of glucose uptake. It was concluded that hot water extract of H. isora activate glucose uptake in L-6 cell line of mouse skeletal muscles. Medknow Publications 2009 /pmc/articles/PMC2839132/ /pubmed/20336200 http://dx.doi.org/10.4103/0973-3930.57349 Text en © International Journal of Diabetes in Developing Countries http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Gupta, R. N.
Pareek, Anil
Suthar, Manish
Rathore, Garvendra S.
Basniwal, Pawan K.
Jain, Deepti
Study of glucose uptake activity of Helicteres isora Linn. fruits in L-6 cell lines
title Study of glucose uptake activity of Helicteres isora Linn. fruits in L-6 cell lines
title_full Study of glucose uptake activity of Helicteres isora Linn. fruits in L-6 cell lines
title_fullStr Study of glucose uptake activity of Helicteres isora Linn. fruits in L-6 cell lines
title_full_unstemmed Study of glucose uptake activity of Helicteres isora Linn. fruits in L-6 cell lines
title_short Study of glucose uptake activity of Helicteres isora Linn. fruits in L-6 cell lines
title_sort study of glucose uptake activity of helicteres isora linn. fruits in l-6 cell lines
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839132/
https://www.ncbi.nlm.nih.gov/pubmed/20336200
http://dx.doi.org/10.4103/0973-3930.57349
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