Cargando…
Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent
Idiopathic pulmonary fibrosis (IPF) is a destructive inflammatory disease with limited therapeutic options. To better understand the inflammatory responses that precede and concur with collagen deposition, we used three models of pulmonary fibrosis and identify a critical mechanistic role for IL-17A...
Autores principales: | Wilson, Mark S., Madala, Satish K., Ramalingam, Thirumalai R., Gochuico, Bernadette R., Rosas, Ivan O., Cheever, Allen W., Wynn, Thomas A. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839145/ https://www.ncbi.nlm.nih.gov/pubmed/20176803 http://dx.doi.org/10.1084/jem.20092121 |
Ejemplares similares
-
The Protective Effects of IL-31RA Deficiency During Bleomycin-Induced Pulmonary Fibrosis
por: Yombo, Dan J. K., et al.
Publicado: (2021) -
Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis
por: Borthwick, Lee A., et al.
Publicado: (2015) -
IL-22 inhibits bleomycin-induced pulmonary fibrosis in association with inhibition of IL-17A in mice
por: Qu, Ziye, et al.
Publicado: (2022) -
IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation
por: Dong, Zhaoxing, et al.
Publicado: (2015) -
Genetic deletion of IL-25 (IL-17E) confers resistance to dextran sulfate sodium-induced colitis in mice
por: Wang, An-Jiang, et al.
Publicado: (2014)