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Essential roles of sphingosine-1–phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema

Systemic exacerbation of allergic responses, in which mast cells play a critical role, results in life-threatening anaphylactic shock. Sphingosine-1–phosphate (S1P), a ligand for a family of G protein–coupled receptors, is a new addition to the repertoire of bioactive lipids secreted by activated ma...

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Detalles Bibliográficos
Autores principales:	Oskeritzian, Carole A., Price, Megan M., Hait, Nitai C., Kapitonov, Dmitri, Falanga, Yves T., Morales, Johanna K., Ryan, John J., Milstien, Sheldon, Spiegel, Sarah
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839150/ https://www.ncbi.nlm.nih.gov/pubmed/20194630 http://dx.doi.org/10.1084/jem.20091513

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