Persistent Expression of FLAG-tagged Micro dystrophin in Nonhuman Primates Following Intramuscular and Vascular Delivery

Animal models for Duchenne muscular dystrophy (DMD) have species limitations related to assessing function, immune response, and distribution of micro- or mini-dystrophins. Nonhuman primates (NHPs) provide the ideal model to optimize vector delivery across a vascular barrier and provide accurate dos...

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Detalles Bibliográficos
Autores principales: Rodino-Klapac, Louise R, Montgomery, Chrystal L, Bremer, William G, Shontz, Kimberly M, Malik, Vinod, Davis, Nancy, Sprinkle, Spencer, Campbell, Katherine J, Sahenk, Zarife, Clark, K Reed, Walker, Christopher M, Mendell, Jerry R, Chicoine, Louis G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839222/
https://www.ncbi.nlm.nih.gov/pubmed/19904237
http://dx.doi.org/10.1038/mt.2009.254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839222/
https://www.ncbi.nlm.nih.gov/pubmed/19904237
http://dx.doi.org/10.1038/mt.2009.254

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