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Distinct expression and ligand-binding profiles of two constitutively active GPR17 splice variants

BACKGROUND AND PURPOSE: In humans and non-human primates, the 7TM receptor GPR17 exists in two isoforms differing only by the length of the N-terminus. Of these, only the short isoform has previously been characterized. Hence, we investigated gene expression and ligand-binding profiles of both splic...

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Detalles Bibliográficos
Autores principales: Benned-Jensen, T, Rosenkilde, MM
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839267/
https://www.ncbi.nlm.nih.gov/pubmed/20148890
http://dx.doi.org/10.1111/j.1476-5381.2009.00633.x