Mathematical Approach for the Assessment of Similarity Factor Using a New Scheme for Calculating Weight

The objective of the present work was to propose a method for calculating weight in the Moore and Flanner Equation. The percentage coefficient of variation in reference and test formulations at each time point was considered for calculating weight. The literature reported data are used to demonstrat...

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Detalles Bibliográficos
Autores principales: Gohel, M. C., Sarvaiya, K. G., Shah, A. R., Brahmbhatt, B. K.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839401/
https://www.ncbi.nlm.nih.gov/pubmed/20336213
http://dx.doi.org/10.4103/0250-474X.54281
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author Gohel, M. C.
Sarvaiya, K. G.
Shah, A. R.
Brahmbhatt, B. K.
author_facet Gohel, M. C.
Sarvaiya, K. G.
Shah, A. R.
Brahmbhatt, B. K.
author_sort Gohel, M. C.
collection PubMed
description The objective of the present work was to propose a method for calculating weight in the Moore and Flanner Equation. The percentage coefficient of variation in reference and test formulations at each time point was considered for calculating weight. The literature reported data are used to demonstrate applicability of the method. The advantages and applications of new approach are narrated. The results show a drop in the value of similarity factor as compared to the approach proposed in earlier work. The scientists who need high accuracy in calculation may use this approach.
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spelling pubmed-28394012010-03-24 Mathematical Approach for the Assessment of Similarity Factor Using a New Scheme for Calculating Weight Gohel, M. C. Sarvaiya, K. G. Shah, A. R. Brahmbhatt, B. K. Indian J Pharm Sci Short Communication The objective of the present work was to propose a method for calculating weight in the Moore and Flanner Equation. The percentage coefficient of variation in reference and test formulations at each time point was considered for calculating weight. The literature reported data are used to demonstrate applicability of the method. The advantages and applications of new approach are narrated. The results show a drop in the value of similarity factor as compared to the approach proposed in earlier work. The scientists who need high accuracy in calculation may use this approach. Medknow Publications 2009 /pmc/articles/PMC2839401/ /pubmed/20336213 http://dx.doi.org/10.4103/0250-474X.54281 Text en © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Gohel, M. C.
Sarvaiya, K. G.
Shah, A. R.
Brahmbhatt, B. K.
Mathematical Approach for the Assessment of Similarity Factor Using a New Scheme for Calculating Weight
title Mathematical Approach for the Assessment of Similarity Factor Using a New Scheme for Calculating Weight
title_full Mathematical Approach for the Assessment of Similarity Factor Using a New Scheme for Calculating Weight
title_fullStr Mathematical Approach for the Assessment of Similarity Factor Using a New Scheme for Calculating Weight
title_full_unstemmed Mathematical Approach for the Assessment of Similarity Factor Using a New Scheme for Calculating Weight
title_short Mathematical Approach for the Assessment of Similarity Factor Using a New Scheme for Calculating Weight
title_sort mathematical approach for the assessment of similarity factor using a new scheme for calculating weight
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839401/
https://www.ncbi.nlm.nih.gov/pubmed/20336213
http://dx.doi.org/10.4103/0250-474X.54281
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