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Three step synthesis of single diastereoisomers of the vicinal trifluoro motif
A three step route to single diastereoisomers of the vicinal trifluoromethyl motif is described. The route starts from either syn- or anti-α,β-epoxy alcohols and takes a direct approach in that each of the three steps introduces a fluorine atom in a regio- and stereo-specific manner. Starting from e...
Autores principales: | Brunet, Vincent A, Slawin, Alexandra M Z, O'Hagan, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839549/ https://www.ncbi.nlm.nih.gov/pubmed/20300509 http://dx.doi.org/10.3762/bjoc.5.61 |
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