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Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer

BACKGROUND: Aurora B kinase is an important mitotic kinase involved in chromosome segregation and cytokinesis. It is overexpressed in many cancers and thus may be an important molecular target for chemotherapy. AZD1152 is the prodrug for AZD1152-HQPA, which is a selective inhibitor of Aurora B kinas...

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Detalles Bibliográficos
Autores principales:	Gully, Christopher P, Zhang, Fanmao, Chen, Jian, Yeung, James A, Velazquez-Torres, Guermarie, Wang, Edward, Yeung, Sai-Ching Jim, Lee, Mong-Hong
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839967/ https://www.ncbi.nlm.nih.gov/pubmed/20175926 http://dx.doi.org/10.1186/1476-4598-9-42

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