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Membrane attack complex inhibitor CD59a protects against focal cerebral ischemia in mice
BACKGROUND: The complement system is a crucial mediator of inflammation and cell lysis after cerebral ischemia. However, there is little information about the exact contribution of the membrane attack complex (MAC) and its inhibitor-protein CD59. METHODS: Transient focal cerebral ischemia was induce...
Autores principales: | Harhausen, Denise, Khojasteh, Uldus, Stahel, Philip F, Morgan, B Paul, Nietfeld, Wilfried, Dirnagl, Ulrich, Trendelenburg, George |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839971/ https://www.ncbi.nlm.nih.gov/pubmed/20202211 http://dx.doi.org/10.1186/1742-2094-7-15 |
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