Early detection of Varicella-Zoster Virus (VZV)-specific T-cells before seroconversion in primary varicella infection: case report

Here we report the case of a 54-year old, immunocompetent German patient with primary varicella whose Varicella-Zoster Virus (VZV)-specific T-cell responses could be detected early in infection and before the onset of seroconversion. This case demonstrates that the detection of VZV-specific T-cells...

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Autores principales: Baiker, Armin, Haase, Rudolf, Eberle, Josef, Pinto, Maria Guadalupe Vizoso, Pfrepper, Klaus-Ingmar, Petrich, Andreas, Deml, Ludwig, Campe, Hartmut, Nitschko, Hans, Jaeger, Gundula
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839977/
https://www.ncbi.nlm.nih.gov/pubmed/20205920
http://dx.doi.org/10.1186/1743-422X-7-54
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author Baiker, Armin
Haase, Rudolf
Eberle, Josef
Pinto, Maria Guadalupe Vizoso
Pfrepper, Klaus-Ingmar
Petrich, Andreas
Deml, Ludwig
Campe, Hartmut
Nitschko, Hans
Jaeger, Gundula
author_facet Baiker, Armin
Haase, Rudolf
Eberle, Josef
Pinto, Maria Guadalupe Vizoso
Pfrepper, Klaus-Ingmar
Petrich, Andreas
Deml, Ludwig
Campe, Hartmut
Nitschko, Hans
Jaeger, Gundula
author_sort Baiker, Armin
collection PubMed
description Here we report the case of a 54-year old, immunocompetent German patient with primary varicella whose Varicella-Zoster Virus (VZV)-specific T-cell responses could be detected early in infection and before the onset of seroconversion. This case demonstrates that the detection of VZV-specific T-cells may under certain circumstances support the diagnosis of a primary varicella infection, as for example in cases of atypical or subclinical varicella or in the absence of detectable VZV DNA in plasma.
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spelling pubmed-28399772010-03-17 Early detection of Varicella-Zoster Virus (VZV)-specific T-cells before seroconversion in primary varicella infection: case report Baiker, Armin Haase, Rudolf Eberle, Josef Pinto, Maria Guadalupe Vizoso Pfrepper, Klaus-Ingmar Petrich, Andreas Deml, Ludwig Campe, Hartmut Nitschko, Hans Jaeger, Gundula Virol J Case Report Here we report the case of a 54-year old, immunocompetent German patient with primary varicella whose Varicella-Zoster Virus (VZV)-specific T-cell responses could be detected early in infection and before the onset of seroconversion. This case demonstrates that the detection of VZV-specific T-cells may under certain circumstances support the diagnosis of a primary varicella infection, as for example in cases of atypical or subclinical varicella or in the absence of detectable VZV DNA in plasma. BioMed Central 2010-03-06 /pmc/articles/PMC2839977/ /pubmed/20205920 http://dx.doi.org/10.1186/1743-422X-7-54 Text en Copyright ©2010 Baiker et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Baiker, Armin
Haase, Rudolf
Eberle, Josef
Pinto, Maria Guadalupe Vizoso
Pfrepper, Klaus-Ingmar
Petrich, Andreas
Deml, Ludwig
Campe, Hartmut
Nitschko, Hans
Jaeger, Gundula
Early detection of Varicella-Zoster Virus (VZV)-specific T-cells before seroconversion in primary varicella infection: case report
title Early detection of Varicella-Zoster Virus (VZV)-specific T-cells before seroconversion in primary varicella infection: case report
title_full Early detection of Varicella-Zoster Virus (VZV)-specific T-cells before seroconversion in primary varicella infection: case report
title_fullStr Early detection of Varicella-Zoster Virus (VZV)-specific T-cells before seroconversion in primary varicella infection: case report
title_full_unstemmed Early detection of Varicella-Zoster Virus (VZV)-specific T-cells before seroconversion in primary varicella infection: case report
title_short Early detection of Varicella-Zoster Virus (VZV)-specific T-cells before seroconversion in primary varicella infection: case report
title_sort early detection of varicella-zoster virus (vzv)-specific t-cells before seroconversion in primary varicella infection: case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839977/
https://www.ncbi.nlm.nih.gov/pubmed/20205920
http://dx.doi.org/10.1186/1743-422X-7-54
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