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Identification and characterization of Dlc1 isoforms in the mouse and study of the biological function of a single gene trapped isoform

BACKGROUND: The Dlc1 (deleted in liver cancer 1) tumour suppressor gene codes for a RhoGTPase activating protein that is found inactivated in many tumour types. Several transcriptional isoforms have been described but the functional significance and tissue distribution of each form is presently poor...

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Detalles Bibliográficos
Autores principales:	Sabbir, Mohammad G, Wigle, Nichola, Loewen, Shauna, Gu, Yuan, Buse, Cordula, Hicks, Geoffrey G, Mowat, Michael RA
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839985/ https://www.ncbi.nlm.nih.gov/pubmed/20199662 http://dx.doi.org/10.1186/1741-7007-8-17

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