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Hepatocellular Carcinoma Displays Distinct DNA Methylation Signatures with Potential as Clinical Predictors

BACKGROUND: Hepatocellular carcinoma (HCC) is characterized by late detection and fast progression, and it is believed that epigenetic disruption may be the cause of its molecular and clinicopathological heterogeneity. A better understanding of the global deregulation of methylation states and how t...

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Detalles Bibliográficos
Autores principales: Hernandez-Vargas, Hector, Lambert, Marie-Pierre, Le Calvez-Kelm, Florence, Gouysse, Géraldine, McKay-Chopin, Sandrine, Tavtigian, Sean V., Scoazec, Jean-Yves, Herceg, Zdenko
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840036/
https://www.ncbi.nlm.nih.gov/pubmed/20305825
http://dx.doi.org/10.1371/journal.pone.0009749