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FasL Gene–Deficient Mice Display a Limited Disruption in Spermatogenesis and Inhibition of Mono-(2-ethylhexyl) Phthalate–Induced Germ Cell Apoptosis

FasL (TNFSF6, CD95L) is hypothesized to trigger testicular germ cell apoptosis that normally occurs during a distinct peripubertal period as well as in response to toxicant-induced Sertoli cell injury. To test this hypothesis, we evaluated the testis of FasL gene–deficient mice (FasL(−/−)) at two di...

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Detalles Bibliográficos
Autores principales: Lin, Yi-Chen, Yao, Pei-Li, Richburg, John H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840219/
https://www.ncbi.nlm.nih.gov/pubmed/20100735
http://dx.doi.org/10.1093/toxsci/kfq015