TRPV2 plays a pivotal role in macrophage particle binding and phagocytosis

Macrophage phagocytosis is critical for defense against pathogens. Whereas many steps of phagocytosis involve ionic flux, the underlying ion channels remain ill-defined. Here, we show that zymosan-, IgG-, and complement-mediated particle binding and phagocytosis are impaired in macrophages lacking t...

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Detalles Bibliográficos
Autores principales: Link, Tiffany M., Park, Una, Vonakis, Becky M., Raben, Daniel M., Soloski, Mark J., Caterina, Michael J.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840267/
https://www.ncbi.nlm.nih.gov/pubmed/20118928
http://dx.doi.org/10.1038/ni.1842

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