Anti-inflammatory effects of hyaluronan in arthritis therapy: Not just for viscosity

Hyaluronic acid (HA) has been widely used for viscosupplementation of diseased or aged articular joints. However, recent investigations have revealed the active anti-inflammatory or chondroprotective effect of HA, suggesting its potential role in attenuation of joint damage. In particular, interacti...

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Detalles Bibliográficos
Autores principales: Masuko, Kayo, Murata, Minako, Yudoh, Kazuo, Kato, Tomohiro, Nakamura, Hiroshi
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840553/
https://www.ncbi.nlm.nih.gov/pubmed/20360891
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author Masuko, Kayo
Murata, Minako
Yudoh, Kazuo
Kato, Tomohiro
Nakamura, Hiroshi
author_facet Masuko, Kayo
Murata, Minako
Yudoh, Kazuo
Kato, Tomohiro
Nakamura, Hiroshi
author_sort Masuko, Kayo
collection PubMed
description Hyaluronic acid (HA) has been widely used for viscosupplementation of diseased or aged articular joints. However, recent investigations have revealed the active anti-inflammatory or chondroprotective effect of HA, suggesting its potential role in attenuation of joint damage. In particular, interactions between HA and other inflammatory mediators are attracting interest. This review summarizes several aspects of recent investigations of the anti-inflammatory effects of HA in arthritis.
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spelling pubmed-28405532010-04-01 Anti-inflammatory effects of hyaluronan in arthritis therapy: Not just for viscosity Masuko, Kayo Murata, Minako Yudoh, Kazuo Kato, Tomohiro Nakamura, Hiroshi Int J Gen Med Review Hyaluronic acid (HA) has been widely used for viscosupplementation of diseased or aged articular joints. However, recent investigations have revealed the active anti-inflammatory or chondroprotective effect of HA, suggesting its potential role in attenuation of joint damage. In particular, interactions between HA and other inflammatory mediators are attracting interest. This review summarizes several aspects of recent investigations of the anti-inflammatory effects of HA in arthritis. Dove Medical Press 2009-07-30 /pmc/articles/PMC2840553/ /pubmed/20360891 Text en © 2009 Masuko et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Masuko, Kayo
Murata, Minako
Yudoh, Kazuo
Kato, Tomohiro
Nakamura, Hiroshi
Anti-inflammatory effects of hyaluronan in arthritis therapy: Not just for viscosity
title Anti-inflammatory effects of hyaluronan in arthritis therapy: Not just for viscosity
title_full Anti-inflammatory effects of hyaluronan in arthritis therapy: Not just for viscosity
title_fullStr Anti-inflammatory effects of hyaluronan in arthritis therapy: Not just for viscosity
title_full_unstemmed Anti-inflammatory effects of hyaluronan in arthritis therapy: Not just for viscosity
title_short Anti-inflammatory effects of hyaluronan in arthritis therapy: Not just for viscosity
title_sort anti-inflammatory effects of hyaluronan in arthritis therapy: not just for viscosity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840553/
https://www.ncbi.nlm.nih.gov/pubmed/20360891
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