Progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia

We report a case of progressive multifocal leukoencephalopathy developing in a fludarabine-naïve patient with chronic lymphocytic leukemia. We suggest that progressive multifocal leukoencephalopathy should be considered in any chronic lymphocytic leukemia patient with unexplained neurological sympto...

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Detalles Bibliográficos
Autores principales: Ooi, Melissa G, Kelly, Peter J, Farrell, Michael, Murphy, Philip, O’Gorman, Peter
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840569/
https://www.ncbi.nlm.nih.gov/pubmed/20360880
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author Ooi, Melissa G
Kelly, Peter J
Farrell, Michael
Murphy, Philip
O’Gorman, Peter
author_facet Ooi, Melissa G
Kelly, Peter J
Farrell, Michael
Murphy, Philip
O’Gorman, Peter
author_sort Ooi, Melissa G
collection PubMed
description We report a case of progressive multifocal leukoencephalopathy developing in a fludarabine-naïve patient with chronic lymphocytic leukemia. We suggest that progressive multifocal leukoencephalopathy should be considered in any chronic lymphocytic leukemia patient with unexplained neurological symptoms. Treatment history does not necessarily require fludarabine. Intrathecal cytosine arabinoside although unsuccessful in this patient, is a therapeutic option to consider in patients experiencing side effects from systemic therapy.
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spelling pubmed-28405692010-04-01 Progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia Ooi, Melissa G Kelly, Peter J Farrell, Michael Murphy, Philip O’Gorman, Peter Int J Gen Med Case Report We report a case of progressive multifocal leukoencephalopathy developing in a fludarabine-naïve patient with chronic lymphocytic leukemia. We suggest that progressive multifocal leukoencephalopathy should be considered in any chronic lymphocytic leukemia patient with unexplained neurological symptoms. Treatment history does not necessarily require fludarabine. Intrathecal cytosine arabinoside although unsuccessful in this patient, is a therapeutic option to consider in patients experiencing side effects from systemic therapy. Dove Medical Press 2009-07-30 /pmc/articles/PMC2840569/ /pubmed/20360880 Text en © 2009 Ooi et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Case Report
Ooi, Melissa G
Kelly, Peter J
Farrell, Michael
Murphy, Philip
O’Gorman, Peter
Progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia
title Progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia
title_full Progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia
title_fullStr Progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia
title_full_unstemmed Progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia
title_short Progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia
title_sort progressive multifocal leukoencephalopathy developing in a fludarabine naïve patient with chronic lymphocytic leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840569/
https://www.ncbi.nlm.nih.gov/pubmed/20360880
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