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The CTLA4 -819 C/T and +49 A/G dimorphisms are associated with Type 1 diabetes in Egyptian children

BACKGROUND: Type 1 diabetes (T1D) is an organ-specific autoimmune disease characterized by T cell-mediated destruction of pancreatic islets. T cell proliferation is negatively regulated by cytotoxic lymphocyte antigen-4 (CTLA-4). CTLA-4 polymorphisms are associated with T1D in some but not all popul...

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Detalles Bibliográficos
Autores principales:	Saleh, Hatem Mohamed, Rohowsky, Nestor, Leski, Michael
Formato:	Texto
Lenguaje:	English
Publicado:	Medknow Publications 2008
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840795/ https://www.ncbi.nlm.nih.gov/pubmed/20300303 http://dx.doi.org/10.4103/0971-6866.45001

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